QuoteIn Bird-Egg Syndrome, cross-reactivity to Hen's egg occurs (2-3). IgE from patients with Bird-Egg Syndrome were shown to recognise a 70 kDa protein in egg yolk and some major allergens in bird feather extract. Chicken serum albumin is the same protein as that designated alpha-livetin in egg yolk. The sera of patients with Bird-Egg Syndrome, pooled with Budgerigar or Hen feather extract and egg yolk extract, led to complete blocking of IgE binding to allergens in egg yolk and bird feather extract. However, IgE from patients with egg white allergy did not react with allergens in egg yolk and bird feather extract, despite strong IgE binding to egg white allergens. These results indicate common epitopes of Budgerigar and Hen feather and egg yolk alpha-livetin, and researchers suggest that alpha-livetin (Chicken serum albumin) leads to a cross-sensitisation and consequently to "Bird-Egg Syndrome" (4-6). This adult type of egg intolerance must be distinguished from the common egg white allergy of atopic children.