Food Allergy Support

Discussion Boards => Main Discussion Board => Topic started by: MandCmama on January 14, 2013, 10:26:39 AM

Title: Egg allergy and flu vaccine
Post by: MandCmama on January 14, 2013, 10:26:39 AM
Ds2 has a severe egg allergy (anaphylaxis), so we haven't done the vaccine with him in the past. Our allergist has stated; however, that in the event of a severe flu outbreak, we would attempt it. As we see her Fri for enviro allergy testing, I'm guessing she'll want to administer the flu shot.  What should I expect? Should I pack enough entertainment for hours?
Title: Re: Egg allergy and flu vaccine
Post by: GingerPye on January 14, 2013, 10:34:22 AM
Both of my kids are considered pretty allergic to egg.  They have had the flu shot for two years now -- we did not do it before that because of recommendations not to do it with egg allergy.  The first year it was done in two parts --- 10% first and then a 30 minute wait; then the remainder and another 30 minute wait.  They did fine.  This year the allergist said we did not have to break it down into parts but we still waited 30 minutes after.  Not a problem. 

Title: Re: Egg allergy and flu vaccine
Post by: twinturbo on January 14, 2013, 10:35:14 AM
The data that's come out in the past two years really opened up flu shots for even severely allergic patients, the old model of scratch, intradermal then split shots has been replaced with essentially straight to split shots possibly graduating to one shot at primary ped.

What to expect? Probably a 10/90 at allergist's office administered by your allergist's nurse. Bring a tablet, book, ER run basics in case you are the percentage of a percentage that reacts. Prepare as you would for an oral challenge. You may get some meds on the preventative side advised to limit exercise or activity for a while.
Title: Re: Egg allergy and flu vaccine
Post by: MandCmama on January 14, 2013, 11:12:24 AM
Thanks ladies! That's kind of what I thought. I'm absolutely terrified though.... I still have PTSD re his reaction @ 9 months.  Most terrifying night of my life  :-/
Title: Re: Egg allergy and flu vaccine
Post by: GingerPye on January 14, 2013, 11:14:37 AM
I KWYM. 

I was so amazed last year when they did okay -- not a hive or an itch or anything! 
Title: Re: Egg allergy and flu vaccine
Post by: Macabre on January 14, 2013, 11:28:40 AM
We we have a thread on this. Can we merge them?
Title: Re: Egg allergy and flu vaccine
Post by: MandCmama on January 14, 2013, 11:40:29 AM
Oh, sure. Sorry!
Title: Re: Egg allergy and flu vaccine
Post by: CMdeux on January 14, 2013, 11:56:51 AM
Quote from: GingerPye on January 14, 2013, 11:14:37 AM
I KWYM. 

I was so amazed last year when they did okay -- not a hive or an itch or anything!

Yes, this!!

I would NEVER have thought that my DD could get a flu shot.  Never.

She did hive up around the injection site, and the local reaction was pretty fierce for a few days-- but that is a really small price to pay in her estimation and ours.  Nothing systemic this year (at least nothing that I recall).


I'll merge this with our other thread in another week or two, if that is okay.
Title: Re: Egg allergy and flu vaccine
Post by: maeve on January 14, 2013, 12:51:28 PM
DD has gotten the flu shot at her pediatrician's the past 2 years.  We wait in the waiting room for 30 minutes after the shot.  She has done wonderfully.  She was able to just get the straight shot at her peds because she tolerated baked egg in a challenge.  Otherwise, I think Hopkins would have advised us to have them administer it.
Title: Re: Egg allergy and flu vaccine
Post by: eggallergymom on January 14, 2013, 08:04:48 PM
My daughter has a severe egg allergy, too. She got the flu shot in two doses at her allergist's office. No problems at all, other than some boredom on her part. ;)
Title: Re: Egg allergy and flu vaccine
Post by: forvictoria on January 15, 2013, 05:58:16 PM
Here's a link about an egg free flu shot, I am not sure if it is available yet but the FDA approved it.
http://thechart.blogs.cnn.com/2012/11/21/fda-approves-new-type-of-flu-shot/ (http://thechart.blogs.cnn.com/2012/11/21/fda-approves-new-type-of-flu-shot/)
Title: Re: Egg allergy and flu vaccine
Post by: hk on January 15, 2013, 07:34:45 PM
We haven't done it yet.  I'm just too nervous.  Dd's allergist thinks she should get it, but her ped disagrees.
Title: Re: Egg allergy and flu vaccine
Post by: joanna5 on January 15, 2013, 08:46:12 PM
We've done flu shots since David was three, as he has asthma and an immune deficiency.  The first three years were all at the hospital with a 10/90 split.  The next was a single shot at Children's.  Last year, he could have done it at the pedi's, but they were out of shots.  This year, he did a single shot at the pedi.  The first year, he had some mild hives at the site, but that was it.  Otherwise, it's gone smoothly.  Well, minus the drama that goes along with any shot, lol.
Title: Re: Egg allergy and flu vaccine
Post by: Macabre on January 15, 2013, 11:01:26 PM
MandC--no worries.  I just know that other thread had some very specific information, but I was looking for it and I couldn't find it (the search on this board is so hard).  CM--I was thinking sooner rather than later to avoid duplication.  Do you know where it is?
Title: Re: Egg allergy and flu vaccine
Post by: CMdeux on January 16, 2013, 01:57:36 AM
I think that the other thread is down in the egg allergy forum. 

Is this it?

Flu vaccination advice for 2011/2012 season (http://foodallergysupport.olicentral.com/index.php/topic,613.0.html)
Title: Re: Egg allergy and flu vaccine
Post by: CMdeux on January 17, 2013, 12:10:08 AM
Hey, though-- HERE is some HUGE news--

FDA approval for cell-culture production of Flu vaccine.


Rapidly Produced Flu Vaccine Wins F.D.A. Approval (http://www.nytimes.com/2013/01/17/business/flublok-a-flu-vaccine-wins-fda-approval.html?_r=0)

It's made using sf9 cells.  These are an insect cell line that is commonly used to produce mammalian proteins using an insect virus as an amplification system.

(I've used this particular system myself to make recombinent proteins for further study, so I know precisely how it works.)

This is egg-free.  There are other proteins of concern used in the cell culture medium, however-- bovine proteins would be of particular concern, and possibly gelatin/other additives.

It's also potentially VERY fast-- much, much faster than the current outdated method of egg culture.

Because the cell line in question does NOT come from a mammalian system, there are far fewer reasonable risks associated with this.  I'd be comfortable with it in a way that green monkey kidney cell lines were never going to make me comfy.  (You're injecting something produced in an immortalized cell line, so...  mostly these are aggressive tumor cell lines.  Theoretically, there should be no residual cellular material remaining after purification... but.)


But I digress.  This is AWESOME news.  It's actually really awesome news for EVERYONE-- because vaccine produced this way is infinitely scalable, and production can start LATER, meaning better matches for circulating strains, meaning that more people are BETTER immunized each season.  This is FANTASTIC news.     :coolbeans:
Title: Re: Egg allergy and flu vaccine
Post by: PurpleCat on January 17, 2013, 02:50:30 PM
Quote from: maeve on January 14, 2013, 12:51:28 PM
DD has gotten the flu shot at her pediatrician's the past 2 years.  We wait in the waiting room for 30 minutes after the shot.  She has done wonderfully.  She was able to just get the straight shot at her peds because she tolerated baked egg in a challenge.  Otherwise, I think Hopkins would have advised us to have them administer it.

Exactly us except not Hopkins!
Title: Re: Egg allergy and flu vaccine
Post by: MandCmama on January 18, 2013, 09:44:50 AM
Allergist out of flu vaccine  :banghead:
On an equally frustrating note, Ds2 is allergic to dogs and everything that grows/blooms in our state!