Sesame PPV? High rate of false positives?

Started by anon668, July 30, 2025, 07:58:24 PM

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anon668

Hi everyone,

I have a food challenge with my allergist scheduled for Tahini in about a month. Sesame is something I've avoided all my life but have never actually eaten before, or even had a reaction, I was just told avoid since I had severe peanut and tree nut allergies at the time.

However, it seems like I've outgrown the nut allergies, and I am highly curious about Sesame, or if I was ever even allergic in the first place.

My SPT was around 7mm and the blood test was 2.7 kU/L. Note that I am positive for essentially every allergen I have tested, even if I'm not necessarily allergic. My allergist seems to think I have a good chance at passing the food challenge.

Does anyone else have experience with sesame allergies, what are your levels, etc? Would be great if I could rule this one out too, after out growing peanuts and tree nuts

anon668

Also aren't Sesame and Peanut allergies closely linked? Ie having one increases your chances of the other. My friend has a severe sesame allergy and he is also very allergic to peanuts.

SilverLining

I've been allergic to peanuts and sesame seeds for about 30 years. SPT at the time was weird. Sometimes it would show I was allergic to everything, and other times nothing. Even the histamine didn't react.

Recently a new allergist wanted me to get tested, since I haven't had any reactions in over a year. Either I've outgrown, or I'm just really careful. No reaction from SPT and blood test said no allergy.

So, I have a peanut food challenge in a few weeks, and sesame a few weeks later.
" No" is a complete sentence!

PurpleCat

My DD is allergic to sesame.  Her reactions have been severe anaphylaxis.  She is also allergic to peanuts and other foods.

hezzier

My son had an allergic reaction to a nut, the allergist included sesame in the testing because it was an "up and coming" allergen.  Even though at the time, he ate Kashi cereals which had sesame in them.  He tested positive, the allergist told us to take it out of his diet.  We got a new allergist and found out that this was bad advice and should have kept it in his diet since he wasn't reacting to it.  Many years later, we moved, new allergist and new testing led to a food challenge...he passed.  We suspect that he was never allergic in the first place.  He has a tree nut allergy, but isn't allergic to peanuts.

I don't have all his test results, but in 2011 it was in between 4-5, in 2016 with the new allergist (who was pretty conservative) felt the number was low enough to do a food challenge.

YouKnowWho

I have a kid who tests positive to everything but only had a handful of allergies (on the flip side his brother tests negative to all on SPT, minor numbers on RAST but further component testing showed gut anaphylactic rxn which has been the case - only sister seems to be consistent on SPTs and RAST).

First two allergists had us pull based on positives (not fun when your kid tests positive to wheat, rye, barley, egg, soy, cows milk, goat milk, corn, rice, oats, sesame, peanuts and tree nuts).  Third allergist started challenging everything we didn't have a known reaction to (minus rye as we couldn't find a source not contaminated with wheat or barley in 2010, plus between wheal and RAST of 6, passing was unlikely). - so his actual list was wheat, rye, barley and egg (he has since outgrown egg and is in a desensitization trial for wheat and barley).
DS1 - Wheat, rye, barley and egg
DS2 - peanuts
DD -  tree nuts, soy and sunflower
Me - bananas, eggplant, many drugs
Southeast USA

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