Eosinophilic Esophagitis(EE)

[AdminCM]

Eosinophilic Esophagitis(EE)

(even though this thread has been extensively edited-- including many post-deletions-- at this point, it is still FILLED with really good information, especially in the first few pages)

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"Can patients with cow's milk-mediated eosinophilic esophagitis tolerate baked milk?"
http://www.aaaai.org/global/latest-research-summaries/Current-JACI-Research/milk-eosinophilic-esophagitis.aspx

cow's milk mediated EoE (CMME)

The authors' findings suggest that a majority of patients with CMME could tolerate baked milk products without recurrence of EoE.

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http://allergynotes.blogspot.com/2014/01/eosinophilic-esophagitis-eoe-top.html

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Eosinophilic Esophagitis—Explaining a "New" Disease
http://www.asthmaallergieschildren.com/2014/01/19/eosinophilic-esophagitis-explaining-a-new-disease/

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A few other board EE threads:

Just diagnosed with Eosinophilic Esophagitis!

EE elecare support

Confusion about EE

Eosinophilic gastroenteritis: Neocate & insurance

EE diagnosis process

EE Videos

Rotation Diets for MFA / Eosinophilic Disorders

EE

[LinksEtc]

http://www.kidswithfoodallergies.org/resourcetopic.php?topic=gastrointestinal-disorders

http://community.kidswithfoodallergies.org/forum/eosinophilic_disorders

http://apfed.org/drupal/drupal/index.php

http://www.cincinnatichildrens.org/health/e/eosinophilic-esophagitis-ee/

http://www.cincinnatichildrens.org/patients/care/stories/patient-stories/ee/default/

http://www.medicinenet.com/eosinophilic_esophagitis/article.htm

http://allergies.about.com/od/foodallergies/a/ee.htm

http://www.nationaljewish.org/healthinfo/conditions/eosinophilic-esophagitis/

http://www.hopkinschildrens.org/Eosinophilic-Esophagitis.aspx

http://www.chop.edu/service/allergy/allergy-and-asthma-information/eosinophilic-esophagitis.html

http://www.aaaai.org/conditions-and-treatments/related-conditions/eosinophilic-esophagitis.aspx

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"As one food allergy resolves, another may develop"
http://www.eurekalert.org/pub_releases/2014-03/chop-aof022814.php

The researchers performed a retrospective analysis of all children seen at CHOP for EoE between 2000 and 2012, a total of 1,375 patients. Of that number, 425 could be shown to have a definite food causing their condition—most commonly milk, egg, soy and wheat. Within that subgroup, 17 patients had developed EoE to a food after having outgrown IgE-mediated allergy to that specific food.

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"Pediatric Eosinophilic Esophagitis: A 10-Year Experience At a Canadian Tertiary Care Centre"
Jason A. Ohayon, MD, Perri R. Tutelman, Jefferson Terry, MD, PhD, Mary E. Sherlock, MB BCh, BAO, PhD
https://aaaai.confex.com/aaaai/2014/webprogram/Paper11128.html

Approximately half of the patients treated with corticosteroids reported symptomatic improvement while over three-quarters of patients reported an improvement on allergy avoidance dietary therapy. At a median follow-up of 31.1 (IQR=81.8-13.4) months, 16 (17%) patients had no change in symptoms from diagnosis, 53 (56%) patients continued to experience symptoms but at a decreased severity, and 17 (18%) experienced a complete resolution of symptoms. Eight (9%) of patients were lost to follow up.

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"Clinical Characteristics Of Eosinophilic Esophagitis - a Case Series Of 30 Patients"
Susana D. Piedade, Diana Silva, Bruno Simões, Ângela Gaspar, Sandra Morgado, Filipa Santos, Mário Morais-Almeida
https://aaaai.confex.com/aaaai/2014/webprogram/Paper12477.html

The most commonly reported symptoms were food impaction (67%), dysphagia (53%), abdominal pain (40%), vomits (37%) and heartburn (37%); the first 2 were significantly more frequent in adults and adolescents. Children's (≤12 years) main complaint was vomits (60%) and failure to thrive occurred in 2 cases. Most had personal history of allergic disease (87%) and aeroallergens sensitization (71%).

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"Patient Ratings Of Various Eosinophilic Esophagitis Treatment Options"
Samantha K. Lin, MD, Neelu Kalra, MD, Gisoo Ghaffari, MD FAAAAI
https://aaaai.confex.com/aaaai/2014/webprogram/Paper11676.html

Rationale: Eosinophilic esophagitis (EoE) can be treated with various combinations of a proton pump inhibitor (PPI), topical steroid (TS), and elimination diet (D). This study assessed which treatments patients were using and sought to determine patient/caregiver ratings of EoE symptoms, response to treatment, and tolerability of therapy.

Use of a topical steroid was associated with significantly higher treatment response ratings and very few side effects.

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"New EoE Test Developed"
http://allergicliving.com/2013/12/05/new-eoe-test-developed/

Researchers at the Cincinnati Children's Hospital have developed a ground breaking diagnostic test for eosinophilic esophagitis, or EoE.

It also differentiated between those whose EoE was in remission and those who didn't have EoE at all.

The test uses a method known as gene expression profiling

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Tweeted by @AllergieVoeding

"Management Guidelines of Eosinophilic Esophagitis in Childhood"
http://mobile.journals.lww.com/jpgn/_layouts/oaks.journals.mobile/articleviewer.aspx?year=2014&issue=01000&article=00027

This position paper of the Eosinophilic Esophagitis Working Group (see Appendix) and the Gastroenterology Committee of ESPGHAN aims at providing practical guidelines for the management of children and adolescents with EoE, based on available evidence where possible. If sufficient evidence is lacking, our recommendations are based on expert opinion and personal practice.

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Tweeted by @AllergyKidsDoc

"ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE)"
http://www.nature.com/ajg/journal/v108/n5/full/ajg201371a.html

Am J Gastroenterol 2013; 108:679–692; doi:10.1038/ajg.2013.71; published online 9 April 2013

Esophageal eosinophilia and eosinophilic esophagitis (EoE) are increasingly recognized and prevalent conditions, which now represent common clinical problems encountered by gastroenterologists, pathologists, and allergists.

In this evidence-based review, recommendations developed by adult and pediatric gastroenterologists are provided for the evaluation and management of these patients.

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Tweeted by @AllergyNet

"Elimination diets in the management of eosinophilic esophagitis"
http://www.dovepress.com/elimination-diets-in-the-management-of-eosinophilic-esophagitis-peer-reviewed-article-JAA

This paper reviews the evidence for all types of dietary therapy in eosinophilic esophagitis.

[SilverLining]

http://blog.foodallergy.org/2014/07/14/researchers-discover-cause-of-eosinophilic-esophagitis/