Differences in interpreting double blind placebo controlled food challenges

[LinksEtc]

Tweeted by @AllergieVoeding

"Differences between observers in interpreting double blind placebo controlled food challenges: A randomized trial."
http://www.ncbi.nlm.nih.gov/pubmed/25403147

51 clinicians reviewing results of 19 DBPCFCs with ambiguous clinical symptoms

Clinicians differ in their interpretation of DBPCFC results when symptoms are ambiguous.

[CMdeux]

GREAT find.   

[TT]

I do admit bringing in parallels from left field.  In that spirit it strikes me as not dissimilar to most of the successful constitutional challenges against drug detection dogs: the handler's ability (or lack of it) to properly interpret the canine's signals and resulting decisions to detain/search.

[LinksEtc]

Tweeted by @Aller_MD


"Allergists' opinions differed on food challenge outcomes"
http://www.healio.com/allergy-immunology/drug-food-insect/news/online/%7Bb3ef0bc8-6e02-4858-b717-8262a6d0848c%7D/allergists-opinions-differed-on-food-challenge-outcomes?utm_content=buffer0c2de&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer

The researchers presented the score sheets of 191 double blind placebo-controlled food challenges for peanut performed in a Dutch academic hospital from 2008 to 2010 to three clinical experts in food allergy.

The occurrence of subjective symptoms [including abdominal complaints and oral allergy symptoms] was associated with disagreement within observers, whereas disagreement was never present when respiratory symptoms occurred.